Bromide

Bromide

SCHEMBL4967971

Br.CCOC(=O)CCN1CCCC1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
MAPT P10636 3/20 0.48
POLB P06746 2/20 0.48
TSHR P16473 5/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
LMNA P02545 5/20 0.45
TP53 P04637 2/20 0.45
HPGD P15428 1/20 0.45
USP2 O75604 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 2/20 0.42
RAB9A P51151 1/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL15818841 0.98 ALDH1A1 (0.52) ALDH1A1MAPTPOLBTSHRL3MBTL1
SCHEMBL8735577 0.98 ALDH1A1 (0.50) ALDH1A1MAPTPOLBTSHRL3MBTL1
SCHEMBL4619736 0.96 ALDH1A1 (0.53) ALDH1A1MAPTPOLBTSHRL3MBTL1
SCHEMBL10256974 0.96 ALDH1A1 (0.53) ALDH1A1MAPTPOLBTSHRL3MBTL1
SCHEMBL3398661 0.94 LMNA (0.46) ALDH1A1MAPTPOLBTSHRL3MBTL1
SCHEMBL18164971 0.92 LMNA (0.45) ALDH1A1MAPTPOLBTSHRL3MBTL1
SCHEMBL674463 0.90 LMNA (0.49) ALDH1A1MAPTPOLBTSHRL3MBTL1
SCHEMBL8957048 0.90 LMNA (0.49) ALDH1A1MAPTPOLBTSHRL3MBTL1
SCHEMBL29700358 0.90 LMNA (0.49) ALDH1A1MAPTPOLBTSHRL3MBTL1
Bromide SCHEMBL741360 0.87 CYP1A2 (0.55) ALDH1A1MAPTPOLBTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2934572-A2 FORMULATIONS AND METHODS FOR STABILIZING PCR REAGENTS Biomatrica, INC. (US) 2015-10-28 EP claimed
WO-2014100755-A2 FORMULATIONS AND METHODS FOR STABILIZING PCR REAGENTS BIOMATRICA, INC. (US) 2014-06-26 WO claimed
EP-4051127-A1 METHODS AND SYSTEMS FOR MENSTRUALOME ANALYSIS NextGen Jane, Inc. (US) 2022-09-07 EP disclosed
EP-4051109-A1 METHODS FOR THE CHARACTERIZATION OF FLUID NextGen Jane, Inc. (US) 2022-09-07 EP disclosed
WO-2021087395-A1 METHODS AND SYSTEMS FOR MENSTRUALOME ANALYSIS NEXTGEN JANE, INC. (US) 2021-05-06 WO disclosed
WO-2021087374-A1 METHODS FOR THE CHARACTERIZATION OF FLUID NEXTGEN JANE, INC. (US) 2021-05-06 WO disclosed
EP-3478365-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF COPD Bodor Laboratories, Inc. (US) 2019-05-08 EP disclosed
WO-2018006001-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF COPD BODOR LABORATORIES, INC. (US) 2018-01-04 WO disclosed
EP-2934572-A2 FORMULATIONS AND METHODS FOR STABILIZING PCR REAGENTS Biomatrica, INC. (US) 2015-10-28 EP disclosed
WO-2014100755-A2 FORMULATIONS AND METHODS FOR STABILIZING PCR REAGENTS BIOMATRICA, INC. (US) 2014-06-26 WO disclosed
EP-1957451-A1 SOFT ANTICHOLINERGIC ZWITTERIONS Bodor, Nicholas S. (US) 2008-08-20 EP disclosed
WO-2007059021-A1 SOFT ANTICHOLINERGIC ZWITTERIONS BODOR NICHOLAS S (US) 2007-05-24 WO disclosed