Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619736 | 0.98 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL10256974 | 0.98 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| Bromide SCHEMBL4967971 | 0.98 | ALDH1A1 (0.48) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| Bromide SCHEMBL15818841 | 0.96 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL3398661 | 0.96 | LMNA (0.46) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL18164971 | 0.94 | LMNA (0.45) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL674463 | 0.92 | LMNA (0.49) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL8957048 | 0.92 | LMNA (0.49) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL29700358 | 0.92 | LMNA (0.49) | ALDH1A1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL1855324 | 0.89 | CYP1A2 (0.53) | ALDH1A1MAPTPOLBTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394898-A | Preparation method of 5-oxohexanoate | 山东智永化工产业技术研究院有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-114394898-A | Preparation method of 5-oxohexanoate | 山东智永化工产业技术研究院有限公司 | 2022-04-26 | — | — | CN | disclosed |
| US-20210253598-A1 | ARYL ANNULATED MACROCYCLIC INDOLE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-08-19 | — | — | US | disclosed |
| US-8728707-B2 | Resist composition and method for producing resist pattern | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |
| US-8728707-B2 | Resist composition and method for producing resist pattern | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |
| US-8568956-B2 | Resist composition and method for producing resist pattern | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-29 | — | — | US | disclosed |
| US-8568956-B2 | Resist composition and method for producing resist pattern | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20130022909-A1 | RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20130022909-A1 | RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20120219899-A1 | RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20120219899-A1 | RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
| EP-0789718-B1 | CATALYST COMPOSITION AND PROCESS FOR THE POLYMERIZATION OF AN OLEFIN | DSM NV (NL) | 1998-04-08 | — | — | EP | disclosed |
| CN-1171794-A | Catalyst composition and process for olefin polymerization | DSM NV (NL) | 1998-01-28 | — | — | CN | disclosed |
| EP-0789718-A1 | CATALYST COMPOSITION AND PROCESS FOR THE POLYMERIZATION OF AN OLEFIN | DSM N.V. (NL) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996013529-A1 | CATALYST COMPOSITION AND PROCESS FOR THE POLYMERIZATION OF AN OLEFIN | DSM N.V. (NL) | 1996-05-09 | — | — | WO | disclosed |
| EP-0409881-B1 | N-HETEROCYCLIC PROPYLIDENE-1,1-BISPHOSPHONIC ACIDS, THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1993-02-10 | — | — | EP | disclosed |
| US-5130304-A | Drugs for calcium metabolism for treatment of osteoporosis or arthritis | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1992-07-14 | — | — | US | disclosed |
| EP-0409881-A1 | N-HETEROCYCLIC PROPYLIDENE-1,1-BISPHOSPHONIC ACIDS, THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION. | LEO PHARM PROD LTD (DK) | 1991-01-30 | — | — | EP | disclosed |
| WO-1989009775-A1 | N-HETEROCYCLIC PROPYLIDENE-1,1-BISPHOSPHONIC ACIDS, THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LØVENS KEMIS (DK) | 1989-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253598-A1 | ARYL ANNULATED MACROCYCLIC INDOLE DERIVATIVES | AHR, IDO1, CCNA1 | ALDH1A1 280/4885MAPT 4034/4885POLB 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.