Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967999 | 1.00 | TRPM4 (0.40) | TRPM4ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL4968542 | 0.86 | HSPA5 (0.50) | ALDH1A1NPSR1MEN1KMT2AHSPA5 | |
| SCHEMBL4968547 | 0.86 | HSPA5 (0.50) | ALDH1A1NPSR1MEN1KMT2AHSPA5 | |
| SCHEMBL4967536 | 0.84 | HTT (0.39) | TRPM4ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL4969103 | 0.84 | HTT (0.39) | TRPM4ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL4969590 | 0.79 | GPR35 (0.38) | ALDH1A1LMNAMEN1KMT2AHSPA5 | |
| SCHEMBL4969584 | 0.79 | GPR35 (0.38) | ALDH1A1LMNAMEN1KMT2AHSPA5 | |
| SCHEMBL4969960 | 0.77 | ALDH1A1 (0.45) | TRPM4ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL13061717 | 0.77 | KDM4E (0.45) | ALDH1A1LMNAMEN1KMT2AHSPA5 | |
| SCHEMBL4969032 | 0.72 | GAA (0.41) | ALDH1A1NPSR1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | TRPM4 2060/4885ALDH1A1 142/4885NPSR1 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.