Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969544 | 0.91 | HTR6 (0.77) | HTR6SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL3152564 | 0.86 | HTR6 (1.00) | HTR6NPSR1L3MBTL1CMA1HTR1A | |
| SCHEMBL4969996 | 0.86 | HTR6 (0.77) | HTR6SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL4969770 | 0.85 | HTR6 (0.78) | HTR6SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL4967538 | 0.85 | HTR6 (0.70) | HTR6SLC6A4 | |
| SCHEMBL4969536 | 0.84 | HTR6 (0.70) | HTR6SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL4979581 | 0.84 | HTR6 (0.79) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL4968330 | 0.83 | HTR6 (0.61) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL4969933 | 0.81 | HTR6 (0.80) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL3148370 | 0.78 | HTR6 (1.00) | HTR6NPSR1L3MBTL1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |