Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.79 |
| ▸ | HTR1D | P28221 | 6/20 | 0.49 |
| ▸ | HTR1B | P28222 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1F | P30939 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969933 | 0.93 | HTR6 (0.80) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3157333 | 0.88 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL4968330 | 0.88 | HTR6 (0.61) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL4969544 | 0.85 | HTR6 (0.77) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL4969996 | 0.84 | HTR6 (0.77) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL4968415 | 0.84 | HTR6 (0.76) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL4969770 | 0.83 | HTR6 (0.78) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL4967538 | 0.83 | HTR6 (0.70) | HTR6 | |
| SCHEMBL4969536 | 0.82 | HTR6 (0.70) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3153770 | 0.81 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |