Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.78 |
| ▸ | HTR1D | P28221 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969536 | 0.95 | HTR6 (0.70) | HTR6HTR1DHTR1AHTR1BADRA2A | |
| SCHEMBL4969996 | 0.94 | HTR6 (0.77) | HTR6HTR1DHTR1AHTR1BADRA2A | |
| SCHEMBL4969544 | 0.91 | HTR6 (0.77) | HTR6HTR1DHTR1AHTR1BADRA2B | |
| SCHEMBL4967538 | 0.89 | HTR6 (0.70) | HTR6HSD17B10SLC6A4 | |
| SCHEMBL3147604 | 0.87 | HTR6 (1.00) | HTR6 | |
| SCHEMBL4968415 | 0.85 | HTR6 (0.76) | HTR6HTR1DHTR1AHTR1BHTR2A | |
| SCHEMBL4979581 | 0.83 | HTR6 (0.79) | HTR6HTR1DHTR1AHTR1BHTR2A | |
| SCHEMBL3156507 | 0.83 | HTR6 (0.91) | HTR6 | |
| SCHEMBL3145090 | 0.81 | HTR6 (1.00) | HTR6 | |
| SCHEMBL4969933 | 0.81 | HTR6 (0.80) | HTR6HTR1DHTR1AHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |