Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17026913 | 0.89 | KMT2A (0.50) | KMT2AMEN1CHRNA7AKT1TMPRSS4 | |
| SCHEMBL4968558 | 0.87 | MEN1 (0.48) | KMT2AMEN1CHRNA7ALDH1A1HTT | |
| SCHEMBL10359093 | 0.81 | KCNMA1 (0.44) | KMT2AMEN1SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL1462428 | 0.80 | MEN1 (1.00) | KMT2AMEN1CHRNA7AKT1TMPRSS4 | |
| SCHEMBL29389109 | 0.80 | MEN1 (1.00) | KMT2AMEN1CHRNA7AKT1TMPRSS4 | |
| SCHEMBL4971171 | 0.80 | GAA (0.57) | KMT2AMEN1SMN1; SMN2HTTMAPT | |
| SCHEMBL4969176 | 0.80 | KMT2A (0.39) | KMT2AMEN1AKT1TMPRSS4ALDH1A1 | |
| SCHEMBL4968141 | 0.78 | KCNMA1 (0.53) | KMT2AMEN1CHRNA7SMN1; SMN2LMNA | |
| SCHEMBL4228884 | 0.77 | MEN1 (0.75) | KMT2AMEN1CHRNA7AKT1TMPRSS4 | |
| SCHEMBL10359687 | 0.76 | HTT (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | KMT2A 1121/4885MEN1 4288/4885CHRNA7 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.