Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968419 | 0.80 | KMT2A (0.66) | KMT2AMEN1HTTTMPRSS4ALDH1A1 | |
| SCHEMBL17026913 | 0.77 | KMT2A (0.50) | KMT2AMEN1HTTTMPRSS4ALDH1A1 | |
| SCHEMBL29316976 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1GPR35TMPRSS4ALDH1A1 | |
| SCHEMBL4969184 | 0.74 | IL1B (0.33) | GPR35NOTUMPTPN5 | |
| SCHEMBL4968978 | 0.71 | HSPA5 (0.49) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL4968965 | 0.71 | HSPA5 (0.49) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL4970600 | 0.70 | HTT (0.39) | KMT2AMEN1HTTGPR35ALDH1A1 | |
| SCHEMBL4968591 | 0.70 | HTT (0.39) | KMT2AMEN1HTTGPR35ALDH1A1 | |
| SCHEMBL4968432 | 0.70 | GAA (0.41) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL4971218 | 0.70 | GAA (0.41) | KMT2AMEN1HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | KMT2A 1121/4885MEN1 4288/4885HTT 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.