Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | USP5 | P45974 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968455 | 0.80 | KDM1A (0.49) | QDPRHTR2C | |
| SCHEMBL808710 | 0.78 | HTR2A (0.46) | USP5HDAC6USP30QDPRHTR2A | |
| SCHEMBL29389392 | 0.78 | HTR2A (0.46) | USP5HDAC6USP30QDPRHTR2A | |
| SCHEMBL13085465 | 0.77 | QDPR (0.59) | USP5HDAC6ADRA1AQDPR | |
| Ammonia Solution, Strong SCHEMBL2142374 | 0.76 | HTR2A (0.44) | USP5HDAC6USP30QDPRHTR2A | |
| Hydrochloric Acid SCHEMBL27914628 | 0.74 | HTR2A (0.47) | USP5HDAC6SCD5USP30HTR2A | |
| SCHEMBL12917832 | 0.74 | GRIA4 (0.43) | USP5HDAC6USP30HTR2AHTR2C | |
| SCHEMBL14817246 | 0.73 | ESR2 (0.53) | CCR2USP5HDAC6ADRA1ASCD5 | |
| SCHEMBL127034 | 0.72 | ACMSD (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL17827776 | 0.72 | HTR2A (0.42) | USP5HDAC6SCD5USP30HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963268-A1 | DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | Neurosearch Sweden AB (SE) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007065655-A1 | DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | NEUROSEARCH SWEDEN AB (SE) | 2007-06-14 | — | — | WO | disclosed |