Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198065 | 0.97 | MEN1 (0.37) | MEN1KMT2ASIRT2MAPTEPHX2 | |
| SCHEMBL2418429 | 0.92 | MEN1 (0.46) | MEN1KMT2ASIRT2MAPTALDH1A1 | |
| SCHEMBL2426776 | 0.90 | MEN1 (0.44) | MEN1KMT2ASIRT2EPHX2ALDH1A1 | |
| SCHEMBL4968679 | 0.89 | MAPK9 (0.44) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7439831 | 0.88 | MEN1 (0.43) | MEN1KMT2ASIRT2MAPTALDH1A1 | |
| SCHEMBL2423188 | 0.82 | KMT2A (0.48) | MEN1KMT2ASIRT2MAPTEPHX2 | |
| SCHEMBL2421018 | 0.82 | ALDH1A1 (0.47) | MEN1KMT2ASIRT2MAPTEPHX2 | |
| SCHEMBL2428331 | 0.81 | KMT2A (0.51) | MEN1KMT2ASIRT2EPHX2ALDH1A1 | |
| SCHEMBL2423593 | 0.81 | KMT2A (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2425330 | 0.80 | MAPK9 (0.51) | MEN1KMT2AEPHX2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |