SCHEMBL496870

SCHEMBL496870

O=c1cnc2ccc3nnccc3c2[nH]1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 1/20 0.36
RPS6KA3 P51812 1/20 0.36
CSNK2A1 P68400 1/20 0.36
PLK3 Q9H4B4 1/20 0.36
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
PKM P14618 1/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4A O75164 2/20 0.30
KDM4C Q9H3R0 2/20 0.30
POLB P06746 1/20 0.30
KDM4B O94953 1/20 0.30
KDM5C P41229 1/20 0.30
KDM5B Q9UGL1 1/20 0.30
KDM3A Q9Y4C1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416592 0.78 MAPT (0.50) MAPKAPK2RPS6KA3CSNK2A1PLK3KDM4E
SCHEMBL2811653 0.74 PKM (0.31) PKM
SCHEMBL11445089 0.71 TYMS (0.44) ALDH1A1KDM4EMAPTMEN1HPGD
SCHEMBL6623124 0.68 ALDH1A1 (0.37) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL17844981 0.67 RXFP1 (0.44) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL22193197 0.67 PDE3B (0.43) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL704132 0.67 MAPKAPK2 (0.39) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL5514516 0.66 MAPT (0.47) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL18839343 0.66 CYP19A1 (0.38) RPS6KA3CSNK2A1PLK3ALDH1A1KDM4E
SCHEMBL18839387 0.66 PDE3B (0.34) MAPTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8106203-B2 Assay methods using chemiluminescent detection of peroxidase LUMIGEN, INC. (US) 2012-01-31 US disclosed
EP-2096110-B1 Acridane-9-dithiocarboxylate derivatives for generating chemiluminescence with a peroxidase LUMIGEN INC (US) 2011-06-22 EP disclosed
US-20090246819-A1 Assay Methods Using Chemiluminescent Detection of Peroxidase LUMIGEN, INC. 2009-10-01 US disclosed
EP-2096110-A1 Acridane-9-dithiocarboxylate derivatives for generating chemiluminescence with a peroxidase LUMIGEN, INC. (US) 2009-09-02 EP disclosed
US-7560556-B2 Assay methods using chemiluminescent detection of peroxidase LUMIGEN, INC. (US) 2009-07-14 US disclosed
EP-1456176-B1 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN INC (US) 2009-03-18 EP disclosed
US-7247726-B2 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. (US) 2007-07-24 US disclosed
EP-1015641-B1 SIMPLIFIED SEQUENTIAL CHEMILUMINESCENT DETECTION LUMIGEN INC (US) 2007-06-13 EP disclosed
US-20050158815-A1 Assay methods using chemiluminescent detection of peroxidase LUMIGEN INC. 2005-07-21 US disclosed
US-6891057-B2 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. (US) 2005-05-10 US disclosed
EP-1019525-A1 CHEMILUMINESCENCE COMPOSITIONS AND METHODS LUMIGEN, INC. (US) 2000-07-19 EP disclosed
EP-1015641-A1 SIMPLIFIED SEQUENTIAL CHEMILUMINESCENT DETECTION LUMIGEN, INC. (US) 2000-07-05 EP disclosed
US-6068979-A IMMOBILIZING TARGETS, CONTACTING WITH LABELED SPECIFIC BINDING PARTNERS FOR EACH TARGET, REACTING WITH SUBSTRATE FOR FIRST LABEL, DETECTING, REACTING WITH SUBSTRATE FOR SECOND ENZYME, DETECTING; ELIMINATES NEED FOR STRIPPING/REPROBING LUMIGEN, INC. (US) 2000-05-30 US disclosed
WO-1999054503-A1 SIMPLIFIED SEQUENTIAL CHEMILUMINESCENT DETECTION LUMIGEN, INC. (US) 1999-10-28 WO disclosed
EP-0938677-A1 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN, INC. (US) 1999-09-01 EP disclosed
US-5922558-A REACTING A PEROXIDASE ENZYME WITH A PEROXIDE AND AT LEAST ONE NOVEL COMPOUND HAVING AN ELECTRON RICH C-C DOUBLE BOND REACTIVE TO PEROXIDASE AND THE PEROXIDE TO PRODUCE AN EXCITED STATE COMPOUND; ALSO USEFUL IN ASSAYS FOR PEROXIDASE ENZYMES LUMIGEN, INC. (US) 1999-07-13 US disclosed
WO-1999014358-A1 CHEMILUMINESCENCE COMPOSITIONS AND METHODS LUMIGEN, INC. (US) 1999-03-25 WO disclosed
US-5843666-A Chemiluminescent detection methods using dual enzyer-labeled binding partners LUMIGEN, INC. (US) 1998-12-01 US disclosed
WO-1998021586-A1 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN, INC. (US) 1998-05-22 WO disclosed
US-5324835-A Useful as luminescent labelling reagents or reagents for determining hydrogen peroxide BIOSENSOR LABORATORIES CO., LTD. (JP) 1994-06-28 US disclosed