Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605009 | 0.85 | CYP1A2 (0.53) | MEN1KMT2AMAPTMAPK1CYP3A4 | |
| SCHEMBL11398684 | 0.85 | CYP1A2 (0.53) | MEN1KMT2AMAPTMAPK1CYP3A4 | |
| SCHEMBL7928173 | 0.85 | CYP1A2 (0.53) | MEN1KMT2AMAPTMAPK1CYP3A4 | |
| SCHEMBL11602083 | 0.83 | MAPT (0.56) | MEN1KMT2AMAPTMAPK1CYP3A4 | |
| SCHEMBL9167944 | 0.83 | MAOA (0.54) | MEN1KMT2AMAPTMAPK1CYP3A4 | |
| SCHEMBL29353964 | 0.81 | MAPT (0.67) | MEN1KMT2AMAPTMAPK1CYP3A4 | |
| SCHEMBL39659 | 0.81 | MAPT (0.67) | MEN1KMT2AMAPTMAPK1CYP3A4 | |
| SCHEMBL9438085 | 0.81 | NPC1 (0.55) | MEN1KMT2AMAPTMAPK1KDM4E | |
| Formaldehyde SCHEMBL27614219 | 0.79 | MAPT (0.64) | MEN1KMT2AMAPTMAPK1CYP3A4 | |
| SCHEMBL10810315 | 0.77 | CSNK2A2 (0.57) | MEN1KMT2AMAPTMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969339-B2 | Compositions and methods for bone formation and modeling | ENZO BIOCHEM, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969339-B2 | Compositions and methods for bone formation and modeling | ENZO BIOCHEM, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | ENZO BIOCHEM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | ENZO BIOCHEM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8367822-B2 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367822-B2 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8105477-B2 | System and method for electrochemical detection of biological compounds | HANDYLAB, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20110039345-A1 | SYSTEM AND METHOD FOR ELECTROCHEMICAL DETECTION OF BIOLOGICAL COMPOUNDS | HANDYLAB, INC. (US) | 2011-02-17 | — | — | US | disclosed |
| US-7820030-B2 | System and method for electrochemical detection of biological compounds | HANDYLAB, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20060207891-A1 | System and method for electrochemical detection of biological compounds | HANDYLAB, INC. (US) | 2006-09-21 | — | — | US | disclosed |
| WO-2004094986-A2 | SYSTEM AND METHOD FOR ELECTROCHEMICAL DETECTION OF BIOLOGICAL COMPOUNDS | HANDYLAB, INC. (US) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | LRP6, BMP6, WNT3A | MEN1 3827/4885KMT2A 4661/4885MAPT 4319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.