Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969646 | 0.86 | POLB (0.61) | POLBLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4970642 | 0.85 | MEN1 (0.43) | POLBLMNAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4969562 | 0.73 | TSHR (0.45) | POLBLMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4968483 | 0.71 | ALDH1A1 (0.66) | POLBLMNACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4970309 | 0.70 | ALDH1A1 (0.48) | POLBALDH1A1TSHRGAAL3MBTL1 | |
| SCHEMBL10358550 | 0.69 | MEN1 (0.40) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL4968655 | 0.68 | MEN1 (0.57) | LMNAALDH1A1TSHRL3MBTL1MEN1 | |
| SCHEMBL1365891 | 0.68 | P2RX4 (0.59) | POLBLMNAALDH1A1TSHRMEN1 | |
| SCHEMBL3072283 | 0.68 | P2RX4 (0.60) | POLBCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19527738 | 0.67 | REN (0.44) | POLBLMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | POLB 4733/4885LMNA 4136/4885CYP1A2 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.