Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | FADS1 | O60427 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424204 | 0.87 | CYP1A2 (0.70) | CYP1A2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL533724 | 0.87 | CYP1A2 (0.70) | CYP1A2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL22025347 | 0.87 | FADS1 (0.59) | CYP1A2NPC1RAB9AKDM4ECASP3 | |
| SCHEMBL1963977 | 0.87 | CYP1A2 (0.70) | CYP1A2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL22065324 | 0.82 | FADS1 (0.54) | CYP1A2NPC1RAB9AKDM4ECASP3 | |
| SCHEMBL5666204 | 0.80 | FADS1 (0.67) | CYP1A2NPC1RAB9AHSD17B10ALDH1A1 | |
| SCHEMBL4954215 | 0.80 | PTGS1 (0.67) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL17744848 | 0.79 | PTGS1 (0.75) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL259352 | 0.79 | MEN1 (0.72) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL31424193 | 0.79 | MEN1 (0.72) | NPC1RAB9AKDM4ECASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094909-A2 | QUINAZOLINONE AND FUSED PYRIMIDINONE COMPOUNDS AND THEIR USE IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-08-07 | — | — | WO | disclosed |