Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | FADS1 | O60427 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424204 | 1.00 | CYP1A2 (0.70) | CYP1A2NPC1RAB9ASMN1; SMN2FADS1 | |
| SCHEMBL22025347 | 0.91 | FADS1 (0.59) | CYP1A2NPC1RAB9ASMN1; SMN2FADS1 | |
| SCHEMBL27758310 | 0.88 | CYP1A2 (0.62) | CYP1A2NPC1RAB9ASMN1; SMN2FADS1 | |
| SCHEMBL4968847 | 0.87 | CYP1A2 (0.65) | CYP1A2NPC1RAB9ASMN1; SMN2FADS1 | |
| SCHEMBL5666204 | 0.87 | FADS1 (0.67) | CYP1A2NPC1RAB9ASMN1; SMN2FADS1 | |
| SCHEMBL22065324 | 0.85 | FADS1 (0.54) | CYP1A2NPC1RAB9ASMN1; SMN2FADS1 | |
| SCHEMBL5900421 | 0.83 | PTGS1 (0.63) | CYP1A2NPC1RAB9ASMN1; SMN2FADS1 | |
| SCHEMBL17744848 | 0.83 | PTGS1 (0.75) | NPC1RAB9ASMN1; SMN2FADS1ALDH1A1 | |
| SCHEMBL13644359 | 0.83 | CYP1A2 (1.00) | CYP1A2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL259352 | 0.83 | MEN1 (0.72) | NPC1RAB9ASMN1; SMN2FADS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-8552009-B2 | Substituted pyrimido 4.5-d pyrimidin-4-one compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. | 2013-10-08 | — | — | US | disclosed |
| US-20110144135-A1 | Compounds for Modulating TRPV3 Function | HYDRA BIOSCIENCES, INC. (US) | 2011-06-16 | — | — | US | disclosed |
| US-7893260-B2 | Substituted quinazolin-4-one compounds for antagonizing TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20100152209-A1 | Compounds for Modulating TRPV3 Function | HYDRA BIOSCIENCES INC. (US) | 2010-06-17 | — | — | US | disclosed |
| EP-1954283-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | Hydra Biosciences, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| WO-2007056124-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | TRPV3, TRPV1, TRPV4 | CYP1A2 3450/4885NPC1 1090/4885RAB9A 2695/4885 |
| US-20100152209-A1 | Compounds for Modulating TRPV3 Function | TRPV3, TRPV1, TRPV4 | CYP1A2 3450/4885NPC1 1090/4885RAB9A 2695/4885 |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | TRPV3, TRPV1, TRPV4 | CYP1A2 3450/4885NPC1 1090/4885RAB9A 2695/4885 |
| US-20110144135-A1 | Compounds for Modulating TRPV3 Function | TRPV3, TRPV1, TRPV4 | CYP1A2 3450/4885NPC1 1090/4885RAB9A 2695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.