Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967412 | 0.87 | CCR3 (0.55) | CCR3MEN1KMT2A | |
| SCHEMBL4965105 | 0.87 | CCR3 (0.49) | CCR3CCR5 | |
| SCHEMBL4969395 | 0.80 | LIPG (0.57) | CCR3CCR5 | |
| SCHEMBL4970299 | 0.78 | CCR3 (0.52) | CCR3KDM4EMEN1KMT2ACCR5 | |
| SCHEMBL4155971 | 0.74 | CCR3 (0.57) | CCR3MEN1KMT2A | |
| SCHEMBL4968313 | 0.74 | HRH1 (0.81) | CCR3 | |
| SCHEMBL4967234 | 0.73 | HRH1 (0.58) | CCR3 | |
| SCHEMBL6704607 | 0.72 | CCR3 (1.00) | CCR3KDM4EMAPK1 | |
| SCHEMBL13698798 | 0.72 | ALDH1A1 (0.59) | KDM4EMEN1KMT2A | |
| SCHEMBL4967140 | 0.72 | HRH1 (0.69) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625114-B1 | Piperidine derivatives for the the treatment of chemokine or H1 mediated diseases | ASTRAZENECA AB (SE) | 2008-08-27 | — | — | EP | disclosed |