SCHEMBL4969192

SCHEMBL4969192

N=C(CC(O)C(=O)OC(=O)CCCCC(=O)O)OC(=O)CCCCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
TSHR P16473 3/20 0.36
NFKB1 P19838 2/20 0.35
PMP22 Q01453 1/20 0.35
SLC22A6 Q4U2R8 2/20 0.32
PAM P19021 2/20 0.32
FFAR4 Q5NUL3 2/20 0.32
FFAR1 O14842 2/20 0.32
ALDH1A1 P00352 2/20 0.32
GPR84 Q9NQS5 3/20 0.31
AKR1B1 P15121 1/20 0.31
CYP2D6 P10635 1/20 0.31
FOLH1 Q04609 1/20 0.31
PPARG P37231 2/20 0.31
PPARD Q03181 2/20 0.31
PPARA Q07869 2/20 0.31
SLC22A8 Q8TCC7 1/20 0.31
TLR2 O60603 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23111822 0.98 TSHR (0.39) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL6767253 0.97 TSHR (0.40) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL23355066 0.90 KDM2A (0.33) LMNAFOLH1
SCHEMBL2019309 0.84 LMNA (0.41) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL3223948 0.83 TSHR (0.43) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL7895528 0.81 TSHR (0.44) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL1580299 0.78 TSHR (0.35) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL1509902 0.77 TSHR (0.35) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL9980489 0.77 NAAA (0.35) ALDH1A1
SCHEMBL5527309 0.76 TSHR (0.33) LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4216929-A1 SUSTAINED RELEASE BIODEGRADABLE INTRACANALICULAR INSERTS COMPRISING A HYDROGEL AND AN ACTIVE AGENT Ocular Therapeutix, Inc. (US) 2023-08-02 EP disclosed
EP-4203996-A1 PENTAVALENT VACCINE AGAINST NEISSERIA MENINGITIDIS COMPRISING A SYNTHETIC MEN A ANTIGEN GlaxoSmithKline Biologicals SA (BE) 2023-07-05 EP disclosed
EP-4009857-A1 BIOERODIBLE CROSS-LINKED HYDROGEL IMPLANTS AND RELATED METHODS OF USE DOSE Medical Corporation (US) 2022-06-15 EP disclosed
WO-2022043238-A1 PENTAVALENT VACCINE AGAINST NEISSERIA MENINGITIDIS COMPRISING A SYNTHETIC MEN A ANTIGEN GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-03-03 WO disclosed
EP-3934696-A1 CARBOCYCLIC DERIVATIVES AND CONJUGATED DERIVATIVES THEREOF, AND THEIR USE IN VACCINES GlaxoSmithKline Biologicals S.A. (BE) 2022-01-12 EP disclosed
EP-3793622-A1 EMBOLIC COMPOSITIONS AND METHODS Incept, LLC (US) 2021-03-24 EP disclosed
WO-2021026214-A1 BIOERODIBLE CROSS-LINKED HYDROGEL IMPLANTS AND RELATED METHODS OF USE DOSE MEDICAL CORPORATION (US) 2021-02-11 WO disclosed
WO-2020243602-A1 BIOERODIBLE CROSS-LINKED HYDROGEL IMPLANTS AND RELATED METHODS OF USE DOSE MEDICAL CORPORATION (US) 2020-12-03 WO disclosed
WO-2020182635-A1 CARBOCYCLIC DERIVATIVES AND CONJUGATED DERIVATIVES THEREOF, AND THEIR USE IN VACCINES GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2020-09-17 WO disclosed
EP-3380077-A1 SHAPE CHANGING DRUG DELIVERY DEVICES AND METHODS Incept, LLC (US) 2018-10-03 EP disclosed
EP-3294212-A1 DRUG DELIVERY FROM HYDROGELS Incept, LLC (US) 2018-03-21 EP disclosed
EP-3229779-A1 HYDROGEL DRUG DELIVERY IMPLANTS Incept, LLC (US) 2017-10-18 EP disclosed
WO-2017091749-A1 SHAPE CHANGING DRUG DELIVERY DEVICES AND METHODS INCEPT, LLC (US) 2017-06-01 WO disclosed
WO-2016183296-A1 DRUG DELIVERY FROM HYDROGELS INCEPT, LLC (US) 2016-11-17 WO disclosed
WO-2016094646-A1 HYDROGEL DRUG DELIVERY IMPLANTS INCEPT, LLC (US) 2016-06-16 WO disclosed
EP-2787973-A1 MEDICAL ORGANOGEL PROCESSES AND COMPOSITIONS INCEPT LLC (US) 2014-10-15 EP disclosed
WO-2013086015-A1 MEDICAL ORGANOGEL PROCESSES AND COMPOSITIONS INCEPT, LLC (US) 2013-06-13 WO disclosed
EP-1979084-A2 SYNTHESIS AND USE OF CROSS-LINKED HYDROPHILIC HOLLOW SPHERES FOR ENCAPSULATING HYDROPHILIC CARGO APPLERA CORPORATION (US) 2008-10-15 EP disclosed
WO-2007102929-A2 SYNTHESIS AND USE OF CROSS-LINKED HYDROPHILIC HOLLOW SPHERES FOR ENCAPSULATING HYDROPHILIC CARGO APPLERA CORPORATION (US) 2007-09-13 WO disclosed