Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 6/20 | 0.45 |
| ▸ | MET | P08581 | 11/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226076 | 0.74 | RPS6KA5 (0.52) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL5613819 | 0.71 | MET (0.48) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL28090927 | 0.71 | RPS6KA5 (0.41) | RPS6KA5METSLC22A12RPS6KA4CDC7 | |
| SCHEMBL9379896 | 0.70 | RPS6KA5 (0.47) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL28832101 | 0.70 | RPS6KA5 (0.41) | RPS6KA5METSLC22A12RPS6KA4CDC7 | |
| SCHEMBL5613917 | 0.68 | MET (0.58) | RPS6KA5METRAPGEF4 | |
| SCHEMBL3828699 | 0.68 | CYP19A1 (0.40) | SLC22A12CDC7CDK2RAPGEF4 | |
| SCHEMBL1472997 | 0.67 | RPS6KA5 (0.57) | RPS6KA5METSLC22A12RPS6KA4CDC7 | |
| SCHEMBL4969251 | 0.67 | FDPS (0.43) | — | |
| Phosphoric Acid SCHEMBL28528859 | 0.66 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784403-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006038773-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-04-13 | — | — | WO | disclosed |