Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.60 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631962 | 0.82 | ALDH1A1 (0.69) | CYP2C9CYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL14161697 | 0.82 | GRIN2B (0.76) | KDM4ECYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5492248 | 0.81 | ALDH1A1 (0.67) | CYP2C9CYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL2959519 | 0.81 | GPR119 (0.74) | KDM4ECYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL3570969 | 0.80 | GFER (0.53) | KDM4ECYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL13648726 | 0.79 | L3MBTL3 (0.72) | KDM4EALDH1A1L3MBTL1MAPTHIF1A | |
| SCHEMBL13648728 | 0.79 | L3MBTL3 (0.72) | KDM4ECYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL16151520 | 0.79 | KDM4E (0.67) | KDM4ECYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL2550326 | 0.78 | L3MBTL3 (0.46) | KDM4EALDH1A1L3MBTL1L3MBTL3MBTD1 | |
| SCHEMBL13200798 | 0.78 | GRIN2B (0.70) | KDM4ECYP2C9CYP2C19ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960359-A1 | NOVEL N-SULFAMOYL-PIPERIDINEAMIDES FOR THE PROPHYLAXIS OR TREATMENT OF OBESITY AND RELATED CONDITIONS | Solvay Pharmaceuticals GmbH (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007065948-A1 | NOVEL N-SULFAMOYL-PIPERIDINEAMIDES FOR THE PROPHYLAXIS OR TREATMENT OF OBESITY AND RELATED CONDITIONS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |