Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426378 | 0.90 | MAPK9 (0.53) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL3479855 | 0.89 | MAPK9 (0.57) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL6021897 | 0.87 | DRD2 (0.54) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2421105 | 0.83 | MAPK9 (0.53) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2425801 | 0.81 | NPC1 (0.51) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL7894066 | 0.80 | MAPK9 (0.51) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL2423054 | 0.80 | MAPK9 (0.59) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL7704876 | 0.79 | ALDH1A1 (0.57) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2421831 | 0.77 | MAPK9 (0.55) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2423073 | 0.77 | MAPK9 (0.55) | MAPK9MAPK10KMT2AMEN1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |