SCHEMBL2916746

SCHEMBL2916746

CCc1cccc(C2CCCCC2)c1O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.53
GABRB2 P47870 1/20 0.53
PTPN5 P54829 4/20 0.44
PTPN2 P17706 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.42
NAAA Q02083 1/20 0.41
KMT2A Q03164 1/20 0.40
OPRL1 P41146 1/20 0.38
PTGS2 P35354 1/20 0.38
FEN1 P39748 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
CEL P19835 1/20 0.37
NUDT1 P36639 1/20 0.36
BACE1 P56817 1/20 0.36
HSP90AA1 P07900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10772495 1.00 GABRA1 (0.53) GABRA1GABRB2PTPN5PTPN2PTGDR2
SCHEMBL8022072 0.98 GABRA1 (0.55) GABRA1GABRB2PTPN5PTPN2PTGDR2
SCHEMBL2047127 0.91 GABRA1 (0.59) GABRA1GABRB2PTPN5PTPN2KMT2A
SCHEMBL4058553 0.86 PTGDR2 (0.41) PTPN5PTPN2PTGDR2NAAAKMT2A
SCHEMBL27728789 0.84 PTGDR2 (0.40) PTPN5PTPN2PTGDR2NAAAKMT2A
SCHEMBL10788064 0.84 ALOX5 (0.44) PTGS2
SCHEMBL11598412 0.84 PTPN5 (0.39) GABRA1GABRB2PTPN5PTPN2PTGDR2
SCHEMBL1385528 0.83 PTGDR2 (0.39) PTPN5PTPN2PTGDR2NAAAKMT2A
SCHEMBL4969723 0.82 PTGDR2 (0.49) PTPN5PTPN2PTGDR2NAAAKMT2A
SCHEMBL3983073 0.82 PTGDR2 (0.49) PTPN5PTPN2PTGDR2NAAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021065275-A1 POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2021-04-08 WO disclosed
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
CN-1307139-C Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2007-03-28 CN disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
CN-1448379-A Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2003-10-15 CN disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed
US-5292956-A For lubricants, mineral oils, polypropylene ETHYL CORPORATION (US) 1994-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 GABRA1 4187/4885GABRB2 4176/4885PTPN5 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.