SCHEMBL4969899

SCHEMBL4969899

CC(CN(C)C(=O)OCC[Si](C)(C)C)N(C(=O)OC(C)(C)C)C1CCCCC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4969906 1.00 HTR2C (0.30) HTR2CSLC6A4
SCHEMBL4971480 0.99
SCHEMBL4971484 0.99
SCHEMBL4970046 0.88 CHRNB2 (0.33)
SCHEMBL4969715 0.76 MEN1 (0.43) SLC6A4
SCHEMBL1424706 0.74 EPHX1 (0.35) HTR2CSLC6A4
SCHEMBL4753063 0.74 EPHX1 (0.35) HTR2CSLC6A4
SCHEMBL1861762 0.74 CTSK (0.45) HTR2CSLC6A4
SCHEMBL1860005 0.74 CTSS (0.41)
SCHEMBL1861759 0.74 CTSK (0.45) HTR2CSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966139-A1 ASPARTIC PROTEASE INHIBITORS Vitae Pharmaceuticals, Inc. (US) 2008-09-10 EP disclosed
WO-2007070201-A1 ASPARTIC PROTEASE INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-06-21 WO disclosed