SCHEMBL4970769

SCHEMBL4970769

CCCCCC(=O)N(C)Cc1cccc(-c2ccc(CCC(=O)O)cc2-c2cccc(OC)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.48
ACHE P22303 1/20 0.48
HSD17B2 P37059 3/20 0.45
FFAR1 O14842 4/20 0.43
LMNA P02545 1/20 0.43
CHEK1 O14757 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42
TSPO P30536 1/20 0.41
OPRM1 P35372 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
EPHX2 P34913 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4969426 0.87 FFAR1 (0.50) BCHEACHEFFAR1
SCHEMBL4970065 0.84 FFAR1 (0.46) FFAR1KMT2A
SCHEMBL4968446 0.84 FFAR1 (0.48) FFAR1KMT2A
SCHEMBL4969532 0.83 FFAR1 (0.44) FFAR1KMT2A
SCHEMBL4969469 0.83 RXRA (0.47) FFAR1
SCHEMBL4971243 0.83 RXRA (0.47) FFAR1KMT2A
SCHEMBL4970904 0.83 MEN1 (0.46) BCHEACHEHSD17B2FFAR1LMNA
SCHEMBL4970077 0.83 FAAH (0.46) FFAR1KMT2A
SCHEMBL4970452 0.83 FFAR1 (0.43) FFAR1KMT2A
SCHEMBL4969511 0.83 RXRA (0.47) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1781274-B1 NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS GALDERMA RES & DEV (FR) 2008-11-05 EP claimed
US-20070207175-A1 Biaromatic compound activators of PPARgamma receptors and cosmetic/pharmaceutical compositions comprised thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2007-09-06 US claimed
EP-1781274-B1 NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS GALDERMA RES & DEV (FR) 2008-11-05 EP disclosed
US-20070207175-A1 Biaromatic compound activators of PPARgamma receptors and cosmetic/pharmaceutical compositions comprised thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070207175-A1 Biaromatic compound activators of PPARgamma receptors and cosmetic/pharmaceutical compositions comprised thereof PPARG, PPARA, PPARD BCHE 2088/4885ACHE 3601/4885HSD17B2 357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.