Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975043 | 0.81 | PRCP (0.44) | MAPTSMN1; SMN2RAB9AIDO1NPC1 | |
| SCHEMBL6716592 | 0.79 | MAPT (0.46) | HTR7MAPTSMN1; SMN2RAB9ACASP3 | |
| SCHEMBL7453036 | 0.77 | ROCK2 (0.54) | HTR7MAPTSMN1; SMN2IDO1PLA2G1B | |
| SCHEMBL7447280 | 0.76 | CHRM1 (0.43) | HTR7MAPTSMN1; SMN2RAB9ACASP3 | |
| Biphenyl SCHEMBL27762344 | 0.73 | MAPK1 (0.49) | HTR7MAPTSMN1; SMN2HTR1AMEN1 | |
| SCHEMBL7445311 | 0.73 | HTR7 (0.41) | HTR7MAPTSMN1; SMN2RAB9ACASP3 | |
| SCHEMBL3323934 | 0.73 | CA12 (0.43) | HTR7MAPTRAB9ACASP3SENP8 | |
| Formamide SCHEMBL28839188 | 0.69 | FLT3 (0.41) | MAPTSMN1; SMN2RAB9ANPC1ADRA2C | |
| Indoline SCHEMBL27976870 | 0.67 | MEN1 (0.45) | MAPTSMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL28240316 | 0.67 | ALDH1A1 (0.58) | HTR7MAPTTDP1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124075-A1 | NOVEL 2,3-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS ANTIPSYCHOTIC AGENTS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-10-16 | — | — | WO | disclosed |