SCHEMBL497155

SCHEMBL497155

CCCCCOC(O)CC(C)C

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
USP2 O75604 1/20 0.38
SPHK1 Q9NYA1 1/20 0.38
HTT P42858 2/20 0.37
LPAR1 Q92633 4/20 0.35
LPAR3 Q9UBY5 4/20 0.35
LPAR2 Q9HBW0 1/20 0.35
MEN1 O00255 1/20 0.34
THRB P10828 1/20 0.34
KMT2A Q03164 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11445080 0.93 TSHR (0.34) DNM1ALDH1A1CNR1CNR2USP2
SCHEMBL27368035 0.83 DNM1 (0.41) DNM1ALDH1A1CNR1CNR2USP2
SCHEMBL1095934 0.79 DNM1 (0.45) DNM1ALDH1A1CNR1CNR2USP2
SCHEMBL27486635 0.79 CES2 (0.38) DNM1ALDH1A1CNR1CNR2USP2
SCHEMBL6033006 0.79 DNM1 (0.42) DNM1USP2SPHK1HTTLPAR1
SCHEMBL24593010 0.78 ODC1 (0.33)
SCHEMBL27925080 0.78 SPHK1 (0.42) DNM1USP2SPHK1HTT
SCHEMBL27695365 0.78 SPHK1 (0.42) DNM1USP2SPHK1HTT
SCHEMBL1978801 0.77 DNM1 (0.48) DNM1USP2SPHK1HTTLPAR1
SCHEMBL23038765 0.77 DNM1 (0.48) DNM1USP2SPHK1HTTLPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8920591-B2 Process for producing electrically conductive bonds between solar cells BASF SE (DE) 2014-12-30 US disclosed
EP-2537188-A1 PROCESS FOR PRODUCING ELECTRICALLY CONDUCTIVE BONDS BETWEEN SOLAR CELLS BASF SE (DE) 2012-12-26 EP disclosed
US-20120312467-A1 PROCESS FOR PRODUCING ELECTRICALLY CONDUCTIVE BONDS BETWEEN SOLAR CELLS BASF SE (DE) 2012-12-13 US disclosed
US-8106045-B2 2-morpholino-4-pyrimidone compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-01-31 US disclosed
WO-2011101788-A1 PROCESS FOR PRODUCING ELECTRICALLY CONDUCTIVE BONDS BETWEEN SOLAR CELLS BASF SE (DE) 2011-08-25 WO disclosed
US-7981642-B2 Polymer extraction methods METABOLIX, INC. (US) 2011-07-19 US disclosed
EP-2266979-A1 2-morpholino-4-pyrimidone compounds Mitsubishi Tanabe Pharma Corporation (JP) 2010-12-29 EP disclosed
EP-2258701-A1 2-morpholino-4-pyrimidone compound Mitsubishi Tanabe Pharma Corporation (JP) 2010-12-08 EP disclosed
US-7795376-B2 Single solvent polymer extraction methods METABOLIX INC. (US) 2010-09-14 US disclosed
US-20100197885-A1 POLYMER EXTRACTION METHODS METABOLIX, INC. 2010-08-05 US disclosed
US-20100196997-A1 POLYMER EXTRACTION METHODS METABOLIX, INC. 2010-08-05 US disclosed
US-7713720-B2 Polymer extraction methods METABOLIX INC. (US) 2010-05-11 US disclosed
US-20100016544-A1 SINGLE SOLVENT POLYMER EXTRACTION METHODS CJ CHEILJEDANG CORPORATION (KR) 2010-01-21 US disclosed
US-20090124618-A1 2-MORPHOLINO-4-PYRIMIDONE COMPOUND MITSUBISHI PHARMA CORPORATION (JP) 2009-05-14 US disclosed
US-20070278157-A1 Polymer Extraction Methods METABOLIX INC. (US) 2007-12-06 US disclosed
EP-1789414-A1 2-MORPHOLINO-4-PYRIMIDONE COMPOUND Mitsubishi Pharma Corporation (JP) 2007-05-30 EP disclosed
WO-2006028290-A1 2-MORPHOLINO-4-PYRIMIDONE COMPOUND MITSUBISHI PHARMA CORPORATION (JP) 2006-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124618-A1 2-MORPHOLINO-4-PYRIMIDONE COMPOUND MAPT, PSEN1, PSEN2 DNM1 172/4885ALDH1A1 3276/4885CNR1 2927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.