Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CBX7 | O95931 | 2/20 | 0.56 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.56 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.56 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970345 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL4968483 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL2627034 | 0.83 | USP2 (0.70) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL14046919 | 0.83 | TSHR (0.63) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL5340163 | 0.82 | HTT (0.56) | ALDH1A1KMT2AMEN1CYP2C19TSHR | |
| SCHEMBL4432608 | 0.81 | KMT2A (0.67) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL5966758 | 0.80 | CCKBR (0.48) | MAPT | |
| SCHEMBL7290163 | 0.80 | MAPT (0.43) | MAPT | |
| SCHEMBL7290156 | 0.80 | MAPT (0.43) | MAPT | |
| SCHEMBL30808661 | 0.79 | KMT2A (0.68) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | ALDH1A1 142/4885KMT2A 1121/4885MEN1 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.