Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 5/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975348 | 0.86 | DPP4 (0.42) | DPP4DPP7KDM4EALDH1A1HPGD | |
| SCHEMBL4975353 | 0.86 | DPP4 (0.42) | DPP4DPP7KDM4EALDH1A1HPGD | |
| SCHEMBL3607883 | 0.83 | GPR119 (0.48) | REN | |
| SCHEMBL3607879 | 0.83 | GPR119 (0.48) | REN | |
| SCHEMBL4974370 | 0.80 | REN (0.41) | DPP4DPP7KDM4EALDH1A1HPGD | |
| SCHEMBL4974097 | 0.79 | REN (0.53) | REN | |
| SCHEMBL4978806 | 0.79 | REN (0.53) | REN | |
| SCHEMBL4970186 | 0.78 | REN (0.55) | REN | |
| SCHEMBL4970187 | 0.78 | REN (0.55) | REN | |
| SCHEMBL4246324 | 0.75 | REN (0.51) | ALDH1A1HPGDSMN1; SMN2RENKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |