Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HK2 | P52789 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651083 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDKDM4EHK2NPC1 | |
| SCHEMBL18713910 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDKDM4EHK2NPC1 | |
| SCHEMBL8709953 | 0.72 | CFTR (0.43) | SMN1; SMN2HPGDKDM4EHK2MEN1 | |
| SCHEMBL4650543 | 0.68 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDKDM4EHK2MEN1 | |
| SCHEMBL9965989 | 0.67 | SIGMAR1 (0.59) | SMN1; SMN2SIGMAR1POLBDRD2ALDH1A1 | |
| SCHEMBL18530070 | 0.64 | ALDH1A1 (0.43) | HPGDKDM4EMEN1KMT2AMAPT | |
| SCHEMBL9875527 | 0.62 | SIGMAR1 (0.51) | SMN1; SMN2HPGDKDM4EMEN1KMT2A | |
| SCHEMBL31678744 | 0.62 | NPC1 (0.51) | SMN1; SMN2HPGDNPC1RAB9AMEN1 | |
| SCHEMBL3898053 | 0.59 | ALDH1A1 (0.42) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL28548234 | 0.56 | HCAR2 (0.53) | SMN1; SMN2HCAR3HCAR2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096391-A1 | NOVEL LACTAMS | BIOSIGNAL LIMITED (AU) | 2017-04-06 | — | — | US | disclosed |
| US-20170096391-A1 | NOVEL LACTAMS | BIOSIGNAL LIMITED (AU) | 2017-04-06 | — | — | US | disclosed |
| US-20170096391-A1 | NOVEL LACTAMS | BIOSIGNAL LIMITED (AU) | 2017-04-06 | — | — | US | disclosed |
| US-9586901-B2 | Lactams | UNILEVER PLC (GB) | 2017-03-07 | — | — | US | disclosed |
| US-9586901-B2 | Lactams | UNILEVER PLC (GB) | 2017-03-07 | — | — | US | disclosed |
| US-9586901-B2 | Lactams | UNILEVER PLC (GB) | 2017-03-07 | — | — | US | disclosed |
| US-20130190377-A1 | Novel Lactams | BIOSIGNAL LIMITED (AU) | 2013-07-25 | — | — | US | disclosed |
| US-20130190377-A1 | Novel Lactams | BIOSIGNAL LIMITED (AU) | 2013-07-25 | — | — | US | disclosed |
| US-20130190377-A1 | Novel Lactams | BIOSIGNAL LIMITED (AU) | 2013-07-25 | — | — | US | disclosed |
| EP-1981844-A1 | NOVEL LACTAMS | Biosignal Limited (AU) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007085042-A1 | NOVEL LACTAMS | BIOSIGNAL LIMITED (AU) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007085042-A1 | NOVEL LACTAMS | BIOSIGNAL LIMITED (AU) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190377-A1 | Novel Lactams | SULT1E1, PGLS, Q6ZSR9 | SMN1; SMN2 3847/4885HPGD 2797/4885KDM4E 828/4885 |
| US-20170096391-A1 | NOVEL LACTAMS | SULT1E1, PGLS, Q6ZSR9 | SMN1; SMN2 3847/4885HPGD 2797/4885KDM4E 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.