Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497356 | 0.87 | HRH3 (0.56) | POLB | |
| SCHEMBL497233 | 0.85 | HRH3 (0.43) | POLBRAB9A | |
| SCHEMBL28767928 | 0.84 | POLB (0.43) | GPR119POLBRAB9APDE4B | |
| SCHEMBL503532 | 0.82 | RORC (0.49) | PDE4B | |
| SCHEMBL1993504 | 0.82 | RORC (0.49) | PDE4B | |
| SCHEMBL503531 | 0.82 | RORC (0.49) | PDE4B | |
| SCHEMBL323889 | 0.81 | USP2 (0.46) | GPR119PDE4B | |
| SCHEMBL497161 | 0.81 | USP2 (0.46) | GPR119PDE4B | |
| SCHEMBL1438341 | 0.80 | ALDH1A1 (0.43) | GPR119POLB | |
| SCHEMBL503547 | 0.80 | NR1H2 (0.45) | GPR119RAB9APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106045-B2 | 2-morpholino-4-pyrimidone compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| CN-101035781-A | 2-morpholino-4-pyrimidone compound | MITSUBISHI PHARMA CORP (JP) | 2007-09-12 | — | — | CN | disclosed |