Trolamine

Trolamine

SCHEMBL497343

CCCCCCCCCCCCOCCCCCCCCCCCC.O=S(=O)(O)O.OCCN(CCO)CCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Trolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.55
▸ THRB P10828 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ MAPT P10636 1/20 0.55
▸ TSHR P16473 2/20 0.45
▸ CES2 O00748 2/20 0.43
▸ USP2 O75604 1/20 0.41
▸ CA1 P00915 8/20 0.40
▸ CA2 P00918 8/20 0.40
▸ CA9 Q16790 7/20 0.40
▸ CA12 O43570 3/20 0.40
▸ CA7 P43166 3/20 0.40
▸ CA14 Q9ULX7 3/20 0.40
▸ CA3 P07451 2/20 0.40
▸ CA4 P22748 2/20 0.40
▸ CA6 P23280 2/20 0.40
▸ CA5A P35218 2/20 0.40
▸ CA5B Q9Y2D0 2/20 0.40
▸ SPHK1 Q9NYA1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL28958108 1.00 MEN1 (0.55) MEN1THRBHTTKMT2AMAPT
Trolamine SCHEMBL10924191 1.00 MEN1 (0.55) MEN1THRBHTTKMT2AMAPT
Trolamine SCHEMBL5962250 0.97 MEN1 (0.52) MEN1THRBHTTKMT2AMAPT
Sulfuric Acid SCHEMBL10924188 0.97 MEN1 (0.52) MEN1THRBHTTKMT2AMAPT
Sulfuric Acid SCHEMBL9773608 0.97 MEN1 (0.52) MEN1THRBHTTKMT2AMAPT
Sulfuric Acid SCHEMBL1490955 0.97 MEN1 (0.52) MEN1THRBHTTKMT2AMAPT
Trolamine SCHEMBL17599677 0.91 HTT (0.46) MEN1THRBHTTKMT2AMAPT
Trolamine SCHEMBL3690709 0.91 MEN1 (0.65) MEN1THRBHTTKMT2AMAPT
Trolamine SCHEMBL27497348 0.91 MEN1 (0.65) MEN1THRBHTTKMT2AMAPT
Trolamine SCHEMBL8858341 0.89 MEN1 (0.51) MEN1THRBHTTKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240415118-A1 Formulation for a Low Viscosity Agricultural Adjuvant Applied in a Spray Syrup Forquimica Agrociencia Ltda (BR) 2024-12-19 — — US claimed
US-12108758-B2 Low viscosity agricultural adjuvant for spraying syrups and method of production Forquimica Agrociencia Ltda (BR) 2024-10-08 — — US claimed
US-20230329232-A1 Low Viscosity Agricultural Adjuvant for Spraying Syrups and Method of Production Forquimica Agrociencia Ltda (BR) 2023-10-19 — — US claimed
CN-114287075-A Conductive composition for secondary battery 广东省皓智科技有限公司 2022-04-05 — — CN claimed
US-20220025735-A1 REDUCING ASPHALTENES IN PRODUCED FLUIDS FROM A WELLBORE CHEVRON U.S.A. INC. (US) 2022-01-27 — — US claimed
US-10266750-B2 Oil recovery compositions and methods thereof CHEVRON U.S.A. INC. (US) 2019-04-23 — — US claimed
EP-2470630-B1 PEARLESCENT CONCENTRATE AND METHOD FOR PRODUCING THE SAME CLARIANT INT LTD (CH) 2017-10-11 — — EP claimed
US-20170058186-A1 OIL RECOVERY COMPOSITIONS AND METHODS THEREOF CHEVRON U.S.A. INC. 2017-03-02 — — US claimed
EP-2730640-B1 Transparent solid cleaning agent DONG A TEACHING MATERIALS CO LTD (KR) 2016-03-30 — — EP claimed
US-9228162-B2 Transparency solid cleaning agent DONG-A TEACHING MATERIALS CO., LTD. (KR) 2016-01-05 — — US claimed
US-20140135249-A1 Transparency solid cleaning agent DONG-A TEACHING MATERIALS CO., LTD. (KR) 2014-05-15 — — US claimed
EP-2730640-A1 Transparent solid cleaning agent Dong-A Teaching Materials Co., Ltd. (KR) 2014-05-14 — — EP claimed
CN-102113970-B Hair cleansing liquid and preparation method and application thereof XU YANPING 2013-03-20 — — CN claimed
CN-102113970-A Hair cleansing liquid and preparation method and application thereof YANPING XU 2011-07-06 — — CN claimed
EP-0764144-A1 ODOR-REDUCING, NUTRIENT-ENHANCING COMPOSITION AND METHOD FOR CULTIVATING EDIBLE FUNGI PYROCAP INTERNATIONAL CORPORATION (US) 1997-03-26 — — EP claimed
US-5574093-A COMPOST PYROCAP INTERNATIONAL CORPORATION (US) 1996-11-12 — — US claimed
WO-1995034521-A1 ODOR-REDUCING, NUTRIENT-ENHANCING COMPOSITION AND METHOD FOR CULTIVATING EDIBLE FUNGI PYROCAP INTERNATIONAL CORPORATION (US) 1995-12-21 — — WO claimed
US-20250262123-A1 EMERGENCY EYE WASH LEBRUN LABS LLC 2025-08-21 — — US disclosed
US-4061602-A Conditioning shampoo composition containing a cationic derivative of a natural gum (such as guar) as the active conditioning ingredient AMERICAN CYANAMID COMPANY (US) 1977-12-06 — — US disclosed
US-3959160-A PACKAGE; FATTY ALCOHOL, ANIONIC SURFACTANT WILKINSON SWORD LIMITED (GB) 1976-05-25 — — US disclosed
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