Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974343 | 1.00 | MTOR (0.34) | MTOR | |
| SCHEMBL4973379 | 0.80 | MTOR (0.33) | MTOR | |
| SCHEMBL4973372 | 0.79 | JAK2 (0.42) | MTOR | |
| SCHEMBL4974288 | 0.79 | FPR2 (0.37) | MTOR | |
| SCHEMBL4974284 | 0.79 | FPR2 (0.37) | MTOR | |
| SCHEMBL22759089 | 0.75 | MTOR (0.50) | MTOR | |
| SCHEMBL22759261 | 0.75 | MTOR (0.50) | MTOR | |
| SCHEMBL32670159 | 0.74 | — | — | |
| SCHEMBL31421948 | 0.74 | — | — | |
| SCHEMBL29341173 | 0.69 | KRAS (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |