Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404098 | 0.84 | MMP2 (0.49) | NPC1RAB9ADPP4MEN1KMT2A | |
| SCHEMBL13623181 | 0.79 | AGTR2 (0.44) | DPP4AGTR2 | |
| SCHEMBL2402151 | 0.79 | AGTR2 (0.44) | DPP4AGTR2 | |
| SCHEMBL2400310 | 0.79 | AGTR2 (0.44) | DPP4AGTR2 | |
| SCHEMBL13623180 | 0.75 | CA12 (0.47) | AGTR2MMP1 | |
| SCHEMBL2402849 | 0.75 | CA12 (0.47) | AGTR2MMP1 | |
| SCHEMBL2400215 | 0.75 | CA12 (0.47) | AGTR2MMP1 | |
| SCHEMBL10402799 | 0.75 | NPC1 (0.54) | NPC1RAB9ADPP4ALDH1A1 | |
| SCHEMBL1248462 | 0.73 | CA12 (0.52) | DPP4AGTR2MMP1 | |
| SCHEMBL1249515 | 0.73 | CA12 (0.52) | DPP4AGTR2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966130-A2 | MODIFIED LYSINE-MIMETIC COMPOUNDS | Zealand Pharma A/S (DK) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007078990-A2 | MODIFIED LYSINE-MIMETIC COMPOUNDS | ZEALAND PHARMA A/S (DK) | 2007-07-12 | — | — | WO | disclosed |