Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 6/20 | 0.44 |
| ▸ | ACE | P12821 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402151 | 1.00 | AGTR2 (0.44) | AGTR2ACESIGMAR1DPP4DPP8 | |
| SCHEMBL2400310 | 1.00 | AGTR2 (0.44) | AGTR2ACESIGMAR1DPP4DPP8 | |
| SCHEMBL4975798 | 0.87 | ALDH1A1 (0.39) | AGTR2 | |
| SCHEMBL2402496 | 0.82 | AGTR2 (0.52) | AGTR2ACEDPP4DPP8DPP7 | |
| Danegaptide SCHEMBL20547963 | 0.82 | MMP2 (0.56) | AGTR2ACEMMP2 | |
| Danegaptide SCHEMBL25694359 | 0.82 | MMP2 (0.56) | AGTR2ACEMMP2 | |
| Danegaptide SCHEMBL2399763 | 0.82 | MMP2 (0.56) | AGTR2ACEMMP2 | |
| SCHEMBL2398925 | 0.82 | AGTR2 (0.52) | AGTR2ACEDPP4DPP8DPP7 | |
| Danegaptide SCHEMBL2399760 | 0.82 | MMP2 (0.56) | AGTR2ACEMMP2 | |
| Danegaptide SCHEMBL29094836 | 0.82 | MMP2 (0.56) | AGTR2ACEMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622496-B2 | antiarrhythmia agents; 1-(2-Amino-acetyl)-4-(benzoylamino)-pyrrolidine-2-carboxylic acid; desirable bioavailability properties | ZEALAND PHARMA A/S (DK) | 2009-11-24 | — | — | US | disclosed |