Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.80 |
| ▸ | CASP7 | P55210 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507400 | 0.96 | ALDH1A1 (0.79) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL11506844 | 0.91 | ALDH1A1 (0.89) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL6677786 | 0.90 | MAPK1 (0.65) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL31333098 | 0.89 | TDP1 (1.00) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL230292 | 0.89 | TDP1 (1.00) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL13862153 | 0.87 | TDP1 (0.66) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL27481715 | 0.87 | MAPK1 (0.65) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL5718635 | 0.84 | MAPK1 (0.77) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL27482796 | 0.84 | MAPK1 (0.57) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 | |
| SCHEMBL5159865 | 0.83 | L3MBTL1 (0.68) | TDP1ALDH1A1MAPK1L3MBTL1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362019-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyrazine compounds | SPELMAN COLLEGE (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362019-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyrazine compounds | SPELMAN COLLEGE (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362019-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyrazine compounds | SPELMAN COLLEGE (US) | 2013-01-29 | — | — | US | disclosed |
| US-8357691-B2 | Synthesis and anti-proliferative effect of benzimidazole derivatives | SPELMAN COLLEGE (US) | 2013-01-22 | — | — | US | disclosed |
| US-8357691-B2 | Synthesis and anti-proliferative effect of benzimidazole derivatives | SPELMAN COLLEGE (US) | 2013-01-22 | — | — | US | disclosed |
| US-8334302-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyridine compounds | SPELMAN COLLEGE (US) | 2012-12-18 | — | — | US | disclosed |
| US-8334302-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyridine compounds | SPELMAN COLLEGE (US) | 2012-12-18 | — | — | US | disclosed |
| US-8334302-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyridine compounds | SPELMAN COLLEGE (US) | 2012-12-18 | — | — | US | disclosed |
| US-8329728-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-c]pyridine compounds | SPELMAN COLLEGE (US) | 2012-12-11 | — | — | US | disclosed |
| US-8329728-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-c]pyridine compounds | SPELMAN COLLEGE (US) | 2012-12-11 | — | — | US | disclosed |
| US-20110152278-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2011-06-23 | — | — | US | disclosed |
| US-7947723-B2 | Synthesis and anti-proliferative effect of benzimidazole derivatives | SPELMAN COLLEGE (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947723-B2 | Synthesis and anti-proliferative effect of benzimidazole derivatives | SPELMAN COLLEGE (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947723-B2 | Synthesis and anti-proliferative effect of benzimidazole derivatives | SPELMAN COLLEGE (US) | 2011-05-24 | — | — | US | disclosed |
| US-20090197889-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2009-08-06 | — | — | US | disclosed |
| US-20090197889-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2009-08-06 | — | — | US | disclosed |
| US-20090197889-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2009-08-06 | — | — | US | disclosed |
| US-7070868-B2 | Organic element for electroluminescent devices | EASTMAN KODAK COMPANY (US) | 2006-07-04 | — | — | US | disclosed |
| WO-2005075599-A1 | ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES | EASTMAN KODAK COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| US-20050170203-A1 | Organic element for electroluminescent devices | EASTMAN KODAK COMPANY | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197889-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | MKI67, PCNA, CCNI | TDP1 1495/4885ALDH1A1 1352/4885MAPK1 1644/4885 |
| US-20110152278-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | MKI67, PCNA, CCNI | TDP1 1495/4885ALDH1A1 1352/4885MAPK1 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.