SCHEMBL5159865

SCHEMBL5159865

O=[N+]([O-])c1cc(-c2ccccc2)ccc1Nc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.68
TDP1 Q9NUW8 3/20 0.65
MAPK1 P28482 3/20 0.65
ALDH1A1 P00352 2/20 0.65
CASP7 P55210 1/20 0.65
HCAR3 P49019 1/20 0.64
MAPT P10636 4/20 0.62
POLB P06746 1/20 0.62
WNK1 Q9H4A3 1/20 0.58
ABCB1 P08183 5/20 0.56
ABCC1 P33527 4/20 0.56
KCNMA1 Q12791 1/20 0.56
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
GFER P55789 1/20 0.51
MYC P01106 1/20 0.51
IDO1 P14902 1/20 0.51
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13304846 0.86 MEN1 (0.69) L3MBTL1TDP1MAPK1ALDH1A1CASP7
SCHEMBL497457 0.83 TDP1 (0.80) L3MBTL1TDP1MAPK1ALDH1A1CASP7
SCHEMBL6642291 0.82 ABCB1 (0.57) L3MBTL1TDP1ALDH1A1HCAR3MAPT
SCHEMBL7981545 0.82 HCAR3 (0.58) HCAR3ABCB1ABCC1KCNMA1CRHBP
SCHEMBL293916 0.82 MAPT (0.72) L3MBTL1TDP1MAPK1ALDH1A1CASP7
SCHEMBL9943157 0.81 L3MBTL1 (0.70) L3MBTL1TDP1MAPK1ALDH1A1CASP7
SCHEMBL1337893 0.81 L3MBTL1 (0.68) L3MBTL1TDP1MAPK1ALDH1A1CASP7
SCHEMBL4938163 0.81 L3MBTL1 (0.68) L3MBTL1TDP1MAPK1ALDH1A1CASP7
SCHEMBL1437915 0.81 HCAR3 (0.68) L3MBTL1TDP1MAPK1ALDH1A1CASP7
SCHEMBL337857 0.81 L3MBTL1 (0.68) L3MBTL1TDP1MAPK1ALDH1A1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 EP disclosed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP disclosed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP disclosed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US disclosed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 EP disclosed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US disclosed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO disclosed