Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970041 | 0.82 | MMP2 (0.39) | SMN1; SMN2HPGD | |
| SCHEMBL4973787 | 0.82 | SMN1; SMN2 (0.33) | PKMSMN1; SMN2GAAHPGD | |
| SCHEMBL4752805 | 0.82 | SMN1; SMN2 (0.33) | PKMSMN1; SMN2GAAHPGD | |
| SCHEMBL4971712 | 0.81 | MMP2 (0.41) | SMN1; SMN2 | |
| SCHEMBL4971492 | 0.81 | MMP2 (0.41) | SMN1; SMN2 | |
| SCHEMBL4975234 | 0.81 | SMN1; SMN2 (0.32) | PKMSMN1; SMN2GAAHPGD | |
| SCHEMBL4972570 | 0.78 | CA12 (0.33) | SMN1; SMN2 | |
| SCHEMBL4974662 | 0.78 | CA12 (0.33) | SMN1; SMN2 | |
| SCHEMBL4973637 | 0.73 | MEN1 (0.31) | — | |
| SCHEMBL4972141 | 0.72 | MAPK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |