Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL559436 | 0.85 | TSHR (0.62) | TSHRFFAR1CYP1A2GABRA1GABRB2 | |
| SCHEMBL10394753 | 0.83 | AKR1B1 (0.42) | TSHRFFAR1CA1CA2CYP1A2 | |
| SCHEMBL7796364 | 0.80 | CA2 (0.48) | TSHRFFAR1CA1CA2CYP1A2 | |
| SCHEMBL29473843 | 0.78 | FFAR1 (0.39) | TSHRFFAR1CA1CA2CYP1A2 | |
| SCHEMBL28739382 | 0.78 | FFAR1 (0.39) | TSHRFFAR1CA1CA2CYP1A2 | |
| SCHEMBL2784586 | 0.77 | TSHR (0.73) | TSHRBCHETYRACHECA1 | |
| SCHEMBL2345180 | 0.76 | FFAR1 (0.37) | TSHRFFAR1CA2CYP1A2LMNA | |
| SCHEMBL632462 | 0.76 | TSHR (0.48) | TSHRBCHETYRACHECA1 | |
| SCHEMBL490576 | 0.76 | PTGS2 (0.47) | TSHRBCHETYRACHECA1 | |
| SCHEMBL4582311 | 0.75 | FFAR1 (0.42) | TSHRFFAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46555-E1 | Deuterated catecholamine derivatives and medicaments comprising said compounds | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2017-09-19 | — | — | US | claimed |
| EP-1991522-A2 | DEUTERATED CATECHOLAMINE DERIVATIVES AND MEDICAMENTS COMPRISING SAID COMPOUNDS | Birds Pharma GmbH Berolina Innovative Research & Development Services (DE) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007093450-A2 | DEUTERATED CATECHOLAMINE DERIVATIVES AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BIRDS PHARMA GMBH BEROLINA INNOVATIVE RESEARCH & DEVELOPMENT SERVICES (DE) | 2007-08-23 | — | — | WO | disclosed |