SCHEMBL490576

SCHEMBL490576

CC(C(=O)O)c1cccc(O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 0.47
PTGS1 P23219 5/20 0.47
CXCL8 P10145 2/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
HIF1A Q16665 3/20 0.45
LMNA P02545 3/20 0.45
HPGD P15428 3/20 0.45
GABRA1 P14867 2/20 0.45
GABRB2 P47870 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
TSHR P16473 2/20 0.45
FAAH O00519 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRG2 P18507 1/20 0.45
SLC6A2 P23975 1/20 0.45
HTR2C P28335 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA5 P31644 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27609913 0.86 CA1 (0.46) PTGS1CA1CA2HIF1ALMNA
SCHEMBL7102472 0.84 PTGS2 (0.47) PTGS2PTGS1CXCL8CA1CA2
SCHEMBL153695 0.83 PTGS2 (0.59) PTGS2PTGS1CXCL8CA1CA2
SCHEMBL3290293 0.82 HPGD (0.50) PTGS2PTGS1CXCL8CA1CA2
SCHEMBL10483833 0.82 CXCL8 (0.46) PTGS1CXCL8CA1CA2HIF1A
SCHEMBL2731013 0.82 PTGS2 (0.57) PTGS2PTGS1CXCL8CA1CA2
SCHEMBL490949 0.82 PTGS2 (0.49) PTGS2PTGS1CXCL8LMNATSHR
Methane SCHEMBL17958768 0.82 PTGS2 (0.57) PTGS2PTGS1CXCL8CA1CA2
SCHEMBL286787 0.81 CXCL8 (0.43) PTGS2PTGS1CXCL8CA1CA2
SCHEMBL6248977 0.81 MMP2 (0.48) PTGS2PTGS1CXCL8CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157854-A Preparation method for synthesizing ADHC-based homopolyester based on dihydroxyaromatic acid carbonate 沈阳工业大学 2025-06-17 CN claimed
US-20250012780-A1 Application of Organic Acids in Urine for Health Management OU YUNG CHUN (TW) 2025-01-09 US claimed
CN-119269659-A Application of urine organic acid in health management 欧湧淳 2025-01-07 CN claimed
CN-118367119-A Organic matter modified carbon-based negative electrode material and manufacturing method thereof 贵州创德新能源科技有限公司 2024-07-19 CN claimed
EP-4206236-A1 COMPOUNDS, THEIR SYNTHESIS AND COMPOSITIONS COMPRISING THE COMPOUNDS FOR ENHANCED DEPOSITION OF POLYMERS ONTO HAIR SURFACES Kao Corporation (JP) 2023-07-05 EP claimed
CN-114177359-B Antibacterial coating and preparation method and application thereof 广东省科学院健康医学研究所 2023-03-24 CN claimed
CN-112210091-B Multifunctional natural polysaccharide repairing adhesive hydrogel, preparation method and application of multifunctional natural polysaccharide repairing adhesive hydrogel in preparation of medicines for treating skin injury 吉林大学 2021-08-10 CN claimed
CN-112210091-A Multifunctional natural polysaccharide repairing adhesive hydrogel, preparation method and application of multifunctional natural polysaccharide repairing adhesive hydrogel in preparation of medicines for treating skin injury 吉林大学 2021-01-12 CN claimed
CN-109705504-B Preparation method of modified polytetrafluoroethylene powder 浙江巨化技术中心有限公司 2020-12-29 CN claimed
CN-110917661-B Method for treating oil-in-water emulsion by using positive electricity enhanced oleophylic hydrophobic three-dimensional porous material 同济大学 2020-12-18 CN claimed
WO-2013063204-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF KEMPHARM, INC. (US) 2013-05-02 WO claimed
WO-2013016668-A2 METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME KEMPHARM INC. (US) 2013-01-31 WO claimed
US-20120142720-A1 Phenylethanoic Acid, Phenylpropanoic Acid and Phenylpropenoic Acid Conjugates and Prodrugs of Hydrocodone, Methods of Making and Use Thereof KEMPHARM, INC. (US) 2012-06-07 US claimed
EP-2448408-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHODS OF MAKING AND USE THEREOF Kempharm, Inc. (US) 2012-05-09 EP claimed
US-20110137235-A1 ULTRASONIC CANCER THERAPY ACCELERATOR TOTO LTD. (JP) 2011-06-09 US claimed
EP-2298327-A1 ANTI-TUMOR AGENT Toto Ltd. (JP) 2011-03-23 EP claimed
WO-2011002995-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHODS OF MAKING AND USE THEREOF KEMPHARM, INC. (US) 2011-01-06 WO claimed
US-20110002991-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF ALTER DOMUS (US) LLC 2011-01-06 US claimed
US-20090297620-A1 Anti-Tumor Agent TOTO LTD. (JP) 2009-12-03 US claimed
US-5686311-A ANALYZING FLUID SAMPLE THE CHILDREN'S MERCY HOSPITAL (US) 1997-11-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142720-A1 Phenylethanoic Acid, Phenylpropanoic Acid and Phenylpropenoic Acid Conjugates and Prodrugs of Hydrocodone, Methods of Making and Use Thereof CYP7A1, CYP2B6, CYP2D6 PTGS2 389/4885PTGS1 154/4885CXCL8 1991/4885
US-20110002991-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF CYP7A1, CYP2B6, CYP2D6 PTGS2 393/4885PTGS1 157/4885CXCL8 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.