SCHEMBL4976507

SCHEMBL4976507

COc1cc2c(cc1-c1cc3c4cc(B5OC(C)(C)C(C)(C)O5)ccc4n(CCC(C)CCCC(C)C)c3cc1OC)c1cc(B3OC(C)(C)C(C)(C)O3)ccc1n2CCC(C)CCCC(C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.35
BACE1 P56817 1/20 0.32
PSEN1 P49768 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4971891 0.91 PSEN1 (0.31) PSEN1
SCHEMBL14029799 0.81 LPL (0.42) CSF1RPSEN1
SCHEMBL4264544 0.81 MAPT (0.37) PSEN1
SCHEMBL4261394 0.80 SIGMAR1 (0.39) PSEN1
SCHEMBL4261403 0.80 MAPT (0.43) PSEN1
SCHEMBL29696454 0.78 LPL (0.37) PSEN1
SCHEMBL4267403 0.77 MAPT (0.39) PSEN1
SCHEMBL4254141 0.75 MAPT (0.39) PSEN1
SCHEMBL4254311 0.74 PSEN1 (0.38) PSEN1
SCHEMBL4254129 0.73 HTR2A (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269461-A1 Polymeric Carbazole Compounds KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-10-30 US disclosed
EP-1966270-A1 POLYMERIC CARBAZOLE COMPOUNDS Koninklijke Philips Electronics N.V. (NL) 2008-09-10 EP disclosed
WO-2007072240-A1 POLYMERIC CARBAZOLE COMPOUNDS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-06-28 WO disclosed