Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267934 | 0.92 | MAPT (0.42) | ALDH1A1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL4261394 | 0.85 | SIGMAR1 (0.39) | ALDH1A1KDM4EMAPT | |
| SCHEMBL4267912 | 0.82 | LMNA (0.36) | MAPTLMNA | |
| SCHEMBL4261403 | 0.82 | MAPT (0.43) | ALDH1A1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL4256948 | 0.81 | PSEN1 (0.42) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL4267403 | 0.77 | MAPT (0.39) | ALDH1A1KDM4EMAPT | |
| SCHEMBL4267813 | 0.76 | SIGMAR1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL31609288 | 0.75 | MEN1 (0.39) | HTR2ATAAR1ALDH1A1LMNAMEN1 | |
| SCHEMBL5999998 | 0.75 | SIGMAR1 (0.48) | MAPTLMNA | |
| SCHEMBL6755578 | 0.75 | SIGMAR1 (0.48) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090242876-A1 | CARBAZOLE COMPOUNDS | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2009-10-01 | — | — | US | disclosed |
| US-20080269461-A1 | Polymeric Carbazole Compounds | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| EP-1966270-A1 | POLYMERIC CARBAZOLE COMPOUNDS | Koninklijke Philips Electronics N.V. (NL) | 2008-09-10 | — | — | EP | disclosed |
| EP-1838671-B1 | 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | KONINKL PHILIPS ELECTRONICS NV (NL) | 2008-06-04 | — | — | EP | disclosed |
| EP-1838671-A2 | 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | Koninklijke Philips Electronics N.V. (NL) | 2007-10-03 | — | — | EP | disclosed |
| WO-2007072240-A1 | POLYMERIC CARBAZOLE COMPOUNDS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006061759-A2 | 9 , 9 ' - AND 2 , 2 ' -SUBSTITUTED 3 , 3 ' -BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090242876-A1 | CARBAZOLE COMPOUNDS | CCNI, IL33, PAICS | HTR2A 3427/4885TAAR1 3124/4885ALDH1A1 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.