Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973595 | 0.88 | RAB9A (0.50) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL1455533 | 0.85 | KDM4E (0.47) | KDM4EHTTRAB9ANPC1PTGER3 | |
| SCHEMBL4975269 | 0.77 | GCK (0.47) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL1454615 | 0.76 | KDM4E (0.43) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL4975567 | 0.74 | MAPT (0.47) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL4976896 | 0.74 | MAPT (0.52) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL1455606 | 0.72 | TAS1R3 (0.40) | KDM4EHTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL1454496 | 0.72 | ALDH1A1 (0.45) | KDM4EHTTRAB9ANPC1PTGER3 | |
| SCHEMBL1454476 | 0.72 | NAMPT (0.41) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL4977002 | 0.71 | PTGS1 (0.56) | KDM4ERAB9ANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |