Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977173 | 0.78 | SLC22A12 (0.41) | SLC22A12MEN1KMT2ASMN1; SMN2SCN9A | |
| SCHEMBL2994131 | 0.73 | SLC22A12 (0.36) | SLC22A12SCN9A | |
| SCHEMBL2998412 | 0.71 | NR1H3 (0.41) | LMNAMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL3002774 | 0.70 | PTGDR2 (0.42) | LMNAMAPTKMT2A | |
| SCHEMBL3003286 | 0.69 | RORC (0.33) | MAPT | |
| SCHEMBL3337435 | 0.68 | HPGD (0.41) | LMNAMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL2989493 | 0.68 | FFAR2 (0.32) | SCN9A | |
| SCHEMBL3003236 | 0.68 | ACLY (0.39) | LMNAMAPTKMT2A | |
| SCHEMBL2999818 | 0.68 | SLC22A12 (0.42) | SLC22A12MEN1KMT2ASCN9A | |
| SCHEMBL3336934 | 0.67 | HPGD (0.40) | LMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124614-A1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2008-10-16 | — | — | WO | disclosed |