Acetone

Acetone

SCHEMBL497758

C=C=O.C=C=O.CC(C)=O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
TSHR P16473 2/20 0.39
THPO P40225 1/20 0.39
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
ALDH1A1 P00352 6/20 0.38
NFKB1 P19838 1/20 0.38
CA1 P00915 2/20 0.36
ALOX15 P16050 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
TDP1 Q9NUW8 3/20 0.35
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CA2 P00918 1/20 0.31
PTGS1 P23219 1/20 0.31
MMP12 P39900 1/20 0.31
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL22409616 1.00
Acetic Acid SCHEMBL2420520 0.87
Acetic Acid SCHEMBL28050593 0.87 FFAR3 (0.58) LMNATSHRTHPOFFAR3LCK
Acetone SCHEMBL10946275 0.86 LMNA (0.40) LMNATSHRFFAR3ALDH1A1TDP1
SCHEMBL28108764 0.81
Acetone SCHEMBL890603 0.80
Methacrylic Acid SCHEMBL17092822 0.78
Methacrylic Acid SCHEMBL8606522 0.78 TDP1 (0.42) LMNAFFAR3LCKFYNALDH1A1
Butanone SCHEMBL10630254 0.78 ALDH1A1 (0.67) LMNATSHRFFAR3ALDH1A1NFKB1
Bicarbonate SCHEMBL25427822 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026974-A Chromonol containing difuran diamine structure and disazo pigment derived from same 江苏丽王科技有限公司 2024-05-14 CN claimed
EP-2048141-B1 OPTICALLY PURE DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES FOR THE PREPARATION OF A MEDICAMENT FOR TREATMENT AND PREVENTION OF VIRAL DISEASES. BEIJING MOLECULE SCIENCE AND TECH CO LTD (CN) 2017-06-14 EP claimed
US-20140141262-A1 VINYL ALCOHOL POLYMERS WITH SILANE SIDE CHAINS AND COMPOSITIONS COMPRISING THE SAME SUN CHEMICAL CORPORATION (US) 2014-05-22 US claimed
EP-2726519-A1 INK AND COATING COMPOSITIONS FOR PACKAGING APPLICATIONS INCLUDING FUNCTIONALIZED HOMOPOLYMERS OR COPOLYMERS OF VINYL ALCOHOLS Sun Chemical Corporation (US) 2014-05-07 EP claimed
EP-2726521-A1 VINYL ALCOHOL POLYMERS WITH SILANE SIDE CHAINS Revolymer Limited (GB) 2014-05-07 EP claimed
WO-2013001313-A1 VINYL ALCOHOL POLYMERS WITH SILANE SIDE CHAINS REVOLYMER LIMITED (GB) 2013-01-03 WO claimed
WO-2013003682-A1 INK AND COATING COMPOSITIONS FOR PACKAGING APPLICATIONS INCLUDING FUNCTIONALIZED HOMOPOLYMERS OR COPOLYMERS OF VINYL ALCOHOLS SUN CHEMICAL CORPORATION (US) 2013-01-03 WO claimed
US-8329902-B2 Optically pure dihydropyrimidine compounds and their uses for the preparation of a medicament for treatment and prevention of viral diseases BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) 2012-12-11 US claimed
US-20100004268-A1 Optically Pure Dihydropyrimidine Compounds and Their Uses for the Preparation of a Medicament for Treatment and Prevention of Viral Diseases BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) 2010-01-07 US claimed
EP-2048141-A1 OPTICAL PURE DIHYDROPYRIMIDINE COMPOUNDS, THEIR USES IN THE MANUFACTURE OF A MEDICAMNENT FOR THE TREATMENT OR THE PREVENTION OF VIROSIS DISEASES Beijing Molecule Science and Technology Co., Ltd. (CN) 2009-04-15 EP claimed
US-6121404-A PREPARED BY REACTING DIKETENE OR EQUIVALENT ACETOACETOXYLATING AGENT WITH AN ORGANOSILICON NUCLEOPHILE IN WHICH THE ORGANOSILICON NUCLEOPHILE IS A HYDROXYORGANOSILANE DOW CORNING CORPORATION (US) 2000-09-19 US claimed
CN-118026974-A Chromonol containing difuran diamine structure and disazo pigment derived from same 江苏丽王科技有限公司 2024-05-14 CN disclosed
WO-2024008939-A1 COMPOSITIONS FOR FIBREBOARDS WITH ENHANCED PROPERTIES UPON FAST-CURING AT LOW TEMPERATURE COVESTRO (NETHERLANDS) B.V. (NL) 2024-01-11 WO disclosed
CN-112105600-B Calixarene compound, curable composition, and cured product DIC株式会社 2023-08-25 CN disclosed
CN-112105600-A Calixarene compound, curable composition, and cured product DIC株式会社 2020-12-18 CN disclosed
US-4170654-A Antihypertensive compositions containing N-heterocyclicalanines and α- MERCK & CO., INC. (US) 1979-10-09 US disclosed
US-4160835-A Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid MERCK & CO., INC. (US) 1979-07-10 US disclosed
US-4156734-A Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid MERCK & CO., INC. (US) 1979-05-29 US disclosed
US-4153715-A Indolyl amino acids useful as antihypertensive agents MERCK & CO., INC. (US) 1979-05-08 US disclosed
US-4065572-A Amino acids and esters thereof useful as antihypertensive agents MERCK & CO., INC. (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004268-A1 Optically Pure Dihydropyrimidine Compounds and Their Uses for the Preparation of a Medicament for Treatment and Prevention of Viral Diseases DPYD, DHPS, DHODH LMNA 2005/4885TSHR 4761/4885THPO 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.