SCHEMBL4978427

SCHEMBL4978427

C=CC(=O)N(CNCCC)CNCCC

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.40
ZDHHC2 Q9UIJ5 2/20 0.40
PAOX Q6QHF9 1/20 0.34
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ADH1B P00325 1/20 0.33
ADH1A P07327 1/20 0.33
ADH7 P40394 1/20 0.33
HPGD P15428 1/20 0.31
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4974645 0.89 ZDHHC20 (0.45) ZDHHC20ZDHHC2PAOXTSHRALDH1A1
SCHEMBL4976090 0.83 ZDHHC20 (0.39) ZDHHC20ZDHHC2TSHRALDH1A1PSMB5
SCHEMBL6658130 0.76 ZDHHC20 (0.37) ZDHHC20ZDHHC2TSHRALDH1A1PSMB5
SCHEMBL8848981 0.75 ZDHHC20 (0.35) ZDHHC20ZDHHC2TSHRALDH1A1
SCHEMBL543056 0.74 ALDH1A1 (0.37) ZDHHC20ZDHHC2TSHRALDH1A1PSMB5
SCHEMBL7153373 0.72 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRALDH1A1PSMB5
SCHEMBL36287 0.72 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRALDH1A1HPGD
Acrylic Acid SCHEMBL4597109 0.72 LMNA (0.50) ZDHHC20ZDHHC2PAOXTSHRALDH1A1
SCHEMBL14880 0.71
SCHEMBL10757580 0.71 ZDHHC20 (0.39) ZDHHC20ZDHHC2TSHRALDH1A1PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2818505-B1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2017-02-01 EP disclosed
EP-2787033-B1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
US-9340663-B2 Rubber composition for tire, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-05-17 US disclosed
EP-2818505-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-12-31 EP disclosed
US-20140371372-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-12-18 US disclosed
US-20140323660-A1 RUBBER COMPOSITION FOR TIRE, AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-10-30 US disclosed
US-8865836-B2 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-10-21 US disclosed
EP-2787033-A1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2014-10-08 EP disclosed
EP-2543702-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2013-09-11 EP disclosed
US-20130012660-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-10 US disclosed
EP-2543702-A1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2013-01-09 EP disclosed
US-7339005-B2 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-04 US disclosed
US-20040152845-A1 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-08-05 US disclosed