Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328844 | 0.87 | HSD11B1 (0.37) | HSD11B1HSD11B2 | |
| SCHEMBL360760 | 0.70 | HSD11B1 (0.48) | HSD11B1HSD11B2 | |
| SCHEMBL328809 | 0.67 | HSD11B1 (0.30) | HSD11B1HSD11B2 | |
| SCHEMBL328875 | 0.64 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL328897 | 0.63 | POLB (0.42) | — | |
| SCHEMBL328946 | 0.63 | HSD11B1 (0.85) | HSD11B1HSD11B2 | |
| SCHEMBL2985358 | 0.58 | MMP13 (0.32) | — | |
| SCHEMBL329103 | 0.55 | HSD11B1 (0.42) | HSD11B1HSD11B2 | |
| SCHEMBL328843 | 0.55 | HSD11B1 (0.52) | HSD11B1HSD11B2 | |
| SCHEMBL60867 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435833-B2 | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme | ABBOTT LABORATORIES (US) | 2008-10-14 | — | — | US | disclosed |
| US-20080076819-A1 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME | ABBOTT LABORATORIES (US) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076819-A1 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME | HSD11B1, HSD11B2, HSD17B1 | HSD11B1 1/4885HSD11B2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.