Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28138 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL818646 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL16538101 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL14760231 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| Octane SCHEMBL18660174 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL26406 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL6534000 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL26538 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL21456807 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL232060 | 0.90 | TSHR (0.42) | LMNATSHRTHRBLPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112393-A | Polsilsesquioxanes, solvent free | PROSOCO, INC. (US) | 1992-05-12 | — | — | US | claimed |
| US-10370499-B2 | Curable organosiloxane oligomer compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180081291-A1 | TONER FORMULATION INCLUDING A SOFTENING AGENT AND METHOD OF PREPARING THE SAME | LEXMARK INTERNATIONAL, INC. | 2018-03-22 | — | — | US | disclosed |
| US-20180081290-A1 | TONER FORMULATION INCLUDING A SOFTENING AGENT AND METHOD OF PREPARING THE SAME | BANK TRUST COMPANY, NATIONAL ASSOCIATION | 2018-03-22 | — | — | US | disclosed |
| EP-3090008-A1 | CURABLE ORGANOSILOXANE OLIGOMER COMPOSITIONS | 3M Innovative Properties Company (US) | 2016-11-09 | — | — | EP | disclosed |
| US-20160319081-A1 | CURABLE ORGANOSILOXANE OLIGOMER COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-11-03 | — | — | US | disclosed |
| WO-2015102979-A1 | CURABLE ORGANOSILOXANE OLIGOMER COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-07-09 | — | — | WO | disclosed |
| US-8129467-B2 | Curing accelerating compound-silica composite material, method for producing curing accelerating compound-silica composite material, curing accelerator, curable resin composition, and electronic component device | HITACHI CHEMICAL CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8013052-B2 | Curable resin, production method thereof, epoxy resin composition, and electronic device | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20090062460-A1 | CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE | HITACHI CHEMICAL CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20030007050-A1 | Curable inkjet printable ink compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2003-01-09 | — | — | US | disclosed |
| US-6461419-B1 | Curable inkjet printable ink compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2002-10-08 | — | — | US | disclosed |
| EP-1238024-A1 | CURABLE INKJET PRINTABLE INK COMPOSITIONS | 3M Innovative Properties Company (US) | 2002-09-11 | — | — | EP | disclosed |
| US-20020086907-A1 | Continuous manufacturing process for organoalkoxysiloxanes | DEGUSSA AG (DE) | 2002-07-04 | — | — | US | disclosed |
| EP-1205505-A2 | Continous process for preparing organoalkoxysiloxanes | Degussa AG (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001032789-A1 | CURABLE INKJET PRINTABLE INK COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-05-10 | — | — | WO | disclosed |
| EP-0552149-A4 | METHOD OF RENDERING MASONRY MATERIALS WATER REPELLENT WITH LOW VOC ORGANOALKOXYSILANES | — | 1993-12-08 | — | — | EP | disclosed |
| EP-0552149-A1 | METHOD OF RENDERING MASONRY MATERIALS WATER REPELLENT WITH LOW VOC ORGANOALKOXYSILANES | PROSOCO, INC. (US) | 1993-07-28 | — | — | EP | disclosed |
| US-5112393-A | Polsilsesquioxanes, solvent free | PROSOCO, INC. (US) | 1992-05-12 | — | — | US | disclosed |
| WO-1992006101-A1 | METHOD OF RENDERING MASONRY MATERIALS WATER REPELLENT WITH LOW VOC ORGANOALKOXYSILANES | PROSOCO, INC. (US) | 1992-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086907-A1 | Continuous manufacturing process for organoalkoxysiloxanes | MED1, C9, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | LMNA 1440/4885TSHR 2316/4885THRB 2263/4885 |
| US-20090062460-A1 | CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE | NCAPH, RAD51, H1-2 | LMNA 794/4885TSHR 3490/4885THRB 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.