SCHEMBL497882

SCHEMBL497882

CC(F)(C=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3915009 0.75
Fluoride SCHEMBL2327409 0.73
SCHEMBL9724351 0.71 LMNA (0.33) THRBLMNA
SCHEMBL20857714 0.71
SCHEMBL25404599 0.69 LMNA (0.38) THRBLMNA
SCHEMBL8189397 0.69 LMNA (0.38) THRBLMNA
SCHEMBL7758191 0.69 LMNA (0.38) THRBLMNA
Water SCHEMBL31538171 0.69 THRB (0.32) THRBLMNA
SCHEMBL27611689 0.69 LMNA (0.38) THRBLMNA
SCHEMBL9540596 0.68 LMNA (0.41) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8106222-B2 Fluorine-containing ether compound FUJIFILM CORPORATION (JP) 2012-01-31 US disclosed
US-20090018350-A1 NOVEL FLUORINE-CONTAINING ETHER COMPOUND FUJIFILM CORPORATION (JP) 2009-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018350-A1 NOVEL FLUORINE-CONTAINING ETHER COMPOUND AFF4, AFF1, AFF2 THRB 2210/4885LMNA 3947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.