SCHEMBL4979140

SCHEMBL4979140

CC1=CCC([Zr](Cc2ccccc2)(Cc2ccccc2)C2=C(C)C(C)=CC2)=C1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7883167 0.75 TP53 (0.31) TP53LMNAPOLB
SCHEMBL4974174 0.72
SCHEMBL7566822 0.68 TP53 (0.31) TP53LMNAPOLB
Hydrochloric Acid SCHEMBL219206 0.66
SCHEMBL7887200 0.66 LMNA (0.32) LMNAPOLB
SCHEMBL4467596 0.66 MAOA (0.36)
SCHEMBL6857157 0.65
SCHEMBL4430885 0.63
Hydrochloric Acid SCHEMBL4978872 0.63 KDM4E (0.31) TP53
(Chloromethyl)Benzene SCHEMBL4470512 0.63 LMNA (0.33) TP53LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1397394-B1 POLYETHYLENE RESINS UNIVATION TECH LLC (US) 2012-05-23 EP disclosed
US-7459509-B2 Polyethylene resins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-12-02 US disclosed
US-20080039606-A9 Polyethylene resins BARRY DAVID B 2008-02-14 US disclosed
US-20070173623-A1 Polyethylene resins UNIVATION TECHNOLOGIES, LLC 2007-07-26 US disclosed
US-7199195-B2 Polyethylene resins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-04-03 US disclosed
EP-1397394-A4 POLYETHYLENE RESINS EXXONMOBIL CHEM PATENTS INC (US) 2005-11-02 EP disclosed
US-20040186251-A1 Polyethylene resine UNIVATION TECHNOLOGIES, LLC 2004-09-23 US disclosed
EP-1397394-A1 POLYETHYLENE RESINS Exxonmobil Chemical Patents Inc. (US) 2004-03-17 EP disclosed
WO-2002090393-A1 POLYETHYLENE RESINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-11-14 WO disclosed