Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566822 | 0.86 | TP53 (0.31) | TP53LMNAPOLB | |
| SCHEMBL7887200 | 0.83 | LMNA (0.32) | LMNAPOLB | |
| SCHEMBL7598618 | 0.78 | — | — | |
| SCHEMBL4979140 | 0.75 | TP53 (0.31) | TP53LMNAPOLB | |
| SCHEMBL5501866 | 0.68 | CA4 (0.31) | — | |
| SCHEMBL1135109 | 0.64 | TP53 (0.31) | TP53LMNAPOLB | |
| SCHEMBL7755339 | 0.64 | TP53 (0.31) | TP53LMNAPOLB | |
| SCHEMBL615604 | 0.63 | TP53 (0.33) | TP53 | |
| SCHEMBL6911396 | 0.59 | TSHR (0.48) | TP53LMNA | |
| SCHEMBL272369 | 0.59 | CALM1 (0.50) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177376-B1 | REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT | TARGOR GMBH (DE) | 2001-01-23 | — | — | US | disclosed |