Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979942 | 0.93 | MGLL (0.38) | NAMPTSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL3982025 | 0.92 | MGLL (0.42) | NAMPTSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL4984400 | 0.92 | MGLL (0.42) | NAMPTSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL3977113 | 0.92 | MGLL (0.42) | NAMPTSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL4979475 | 0.92 | MGLL (0.42) | NAMPTSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL4980233 | 0.90 | SLC1A3 (0.40) | NAMPTSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL4983200 | 0.89 | LMNA (0.43) | L3MBTL1SLC1A3SLC1A2SLC1A1SMN1; SMN2 | |
| SCHEMBL4979553 | 0.88 | CYP1A2 (0.44) | SLC1A3SLC1A2SLC1A1METAP1SRD5A1 | |
| SCHEMBL4980970 | 0.86 | KDM4E (0.46) | L3MBTL1SLC1A3SLC1A2SLC1A1METAP1 | |
| SCHEMBL4980961 | 0.85 | LMNA (0.42) | SLC1A3SLC1A2SLC1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096875-A1 | THIOUREA COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096875-A1 | THIOUREA COMPOUNDS | TPMT, HAVCR2, ETV6 | NAMPT 2150/4885L3MBTL1 822/4885SLC1A3 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.